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Cigarette smoking-associated isoform switching and 3′ UTR lengthening via alternative polyadenylation

Cigarette smoking induces a profound transcriptomic and systemic inflammatory response. Previous studies have focused on gene level differential expression of smoking, but the genome-wide effects of smoking on alternative isoform regulation have not yet been described. We conducted RNA sequencing in...

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Detalles Bibliográficos
Autores principales: Xu, Zhonghui, Platig, John, Lee, Sool, Boueiz, Adel, Chase, Rob, Jain, Dhawal, Gregory, Andrew, Suryadevara, Rahul, Berman, Seth, Bowler, Russell, Hersh, Craig P., Laederach, Alain, Castaldi, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722433/
https://www.ncbi.nlm.nih.gov/pubmed/34763026
http://dx.doi.org/10.1016/j.ygeno.2021.11.004