Intracellular NAD(+) Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation

Nicotinamide adenine dinucleotide (NAD(+)) is an important cofactor in many redox and non-redox NAD(+)-consuming enzyme reactions. Intracellular NAD(+) level steadily declines with age, but its role in the innate immune potential of myeloid cells remains elusive. In this study, we explored whether N...

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Detalles Bibliográficos
Autores principales: Shim, Do-Wan, Cho, Hyo-Joung, Hwang, Inhwa, Jung, Taek-Yeol, Kim, Hyun-Seok, Ryu, Ju Hee, Yu, Je-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722528/
https://www.ncbi.nlm.nih.gov/pubmed/34987507
http://dx.doi.org/10.3389/fimmu.2021.765477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722528/
https://www.ncbi.nlm.nih.gov/pubmed/34987507
http://dx.doi.org/10.3389/fimmu.2021.765477

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