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Intracellular NAD(+) Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation

Nicotinamide adenine dinucleotide (NAD(+)) is an important cofactor in many redox and non-redox NAD(+)-consuming enzyme reactions. Intracellular NAD(+) level steadily declines with age, but its role in the innate immune potential of myeloid cells remains elusive. In this study, we explored whether N...

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Detalles Bibliográficos
Autores principales:	Shim, Do-Wan, Cho, Hyo-Joung, Hwang, Inhwa, Jung, Taek-Yeol, Kim, Hyun-Seok, Ryu, Ju Hee, Yu, Je-Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722528/ https://www.ncbi.nlm.nih.gov/pubmed/34987507 http://dx.doi.org/10.3389/fimmu.2021.765477

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