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Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants

Vaccine hesitancy and continuing emergence of SARS-CoV-2 variants of concern that may escape vaccine-induced immune responses highlight the urgent need for effective COVID-19 therapeutics. Monoclonal antibodies used in the clinic have varying efficacies against distinct SARS-CoV-2 variants; thus, th...

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Detalles Bibliográficos
Autores principales: Zhang, Lianghui, Dutta, Soumajit, Xiong, Shiqin, Chan, Matthew, Chan, Kui K., Fan, Timothy M., Bailey, Keith L., Lindeblad, Matthew, Cooper, Laura M., Rong, Lijun, Gugliuzza, Anthony F., Shukla, Diwakar, Procko, Erik, Rehman, Jalees, Malik, Asrar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722596/
https://www.ncbi.nlm.nih.gov/pubmed/34981059
http://dx.doi.org/10.1101/2021.12.21.473668