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SARS-CoV-2 spike conformation determines plasma neutralizing activity

Numerous safe and effective COVID-19 vaccines have been developed that utilize various delivery technologies and engineering strategies. The influence of the SARS-CoV-2 spike (S) glycoprotein conformation on antibody responses induced by vaccination or infection in humans remains unknown. To address...

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Detalles Bibliográficos
Autores principales: Bowen, John E., Walls, Alexandra C., Joshi, Anshu, Sprouse, Kaitlin R., Stewart, Cameron, Tortorici, M. Alejandra, Franko, Nicholas M., Logue, Jennifer K., Mazzitelli, Ignacio G., Tiles, Sasha W, Ahmed, Kumail, Shariq, Asefa, Snell, Gyorgy, Iqbal, Najeeha Talat, Geffner, Jorge, Bandera, Alessandra, Gori, Andrea, Grifantini, Renata, Chu, Helen Y., Van Voorhis, Wesley C., Corti, Davide, Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722597/
https://www.ncbi.nlm.nih.gov/pubmed/34981060
http://dx.doi.org/10.1101/2021.12.19.473391