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S-palmitoylation and sterol interactions mediate antiviral specificity of IFITM isoforms

Interferon-induced transmembrane proteins (IFITM1, 2 and 3) are important antiviral proteins that are active against many viruses, including influenza A virus (IAV), dengue virus (DENV), Ebola virus (EBOV), Zika virus (ZIKV) and severe acute respiratory syndrome coronavirus (SARS-CoV). IFITMs exhibi...

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Detalles Bibliográficos
Autores principales: Das, Tandrila, Yang, Xinglin, Lee, Hwayoung, Garst, Emma, Valencia, Estefania, Chandran, Kartik, Im, Wonpil, Hang, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722608/
https://www.ncbi.nlm.nih.gov/pubmed/34981045
http://dx.doi.org/10.21203/rs.3.rs-1179000/v1