Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation

Background: Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can be used as a source for cell delivery to remuscularize the heart after myocardial infarction. Despite their therapeutic potential, the emergence of ventricular arrhythmias has limited their application. We previously develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Pezhouman, Arash, Nguyen, Ngoc B., Sercel, Alexander J., Nguyen, Thang L., Daraei, Ali, Sabri, Shan, Chapski, Douglas J., Zheng, Melton, Patananan, Alexander N., Ernst, Jason, Plath, Kathrin, Vondriska, Thomas M., Teitell, Michael A., Ardehali, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722677/
https://www.ncbi.nlm.nih.gov/pubmed/34988079
http://dx.doi.org/10.3389/fcell.2021.787684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722677/
https://www.ncbi.nlm.nih.gov/pubmed/34988079
http://dx.doi.org/10.3389/fcell.2021.787684

Ejemplares similares