Cargando…

Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation

Background: Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can be used as a source for cell delivery to remuscularize the heart after myocardial infarction. Despite their therapeutic potential, the emergence of ventricular arrhythmias has limited their application. We previously develop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pezhouman, Arash, Nguyen, Ngoc B., Sercel, Alexander J., Nguyen, Thang L., Daraei, Ali, Sabri, Shan, Chapski, Douglas J., Zheng, Melton, Patananan, Alexander N., Ernst, Jason, Plath, Kathrin, Vondriska, Thomas M., Teitell, Michael A., Ardehali, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722677/ https://www.ncbi.nlm.nih.gov/pubmed/34988079 http://dx.doi.org/10.3389/fcell.2021.787684

Ejemplares similares

c-JUN is a barrier in hESC to cardiomyocyte transition
por: Zhong, Hui, et al.
Publicado: (2023)

From MEFs to Matrigel 3: Passaging hESCs from Matrigel onto Matrigel
por: Zhang, Jin, et al.
Publicado: (2008)

hESC-Derived Cardiomyocytes Electrically Couple and Suppress Arrhythmias in Injured Hearts
por: Shiba, Yuji, et al.
Publicado: (2012)

Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells
por: Dawson, Emma R., et al.
Publicado: (2020)

hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts
por: Todorova, Dilyana, et al.
Publicado: (2020)

Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes
por: Macrae, Robyn G C, et al.
Publicado: (2022)

Quantification of the morphological characteristics of hESC colonies
por: Orozco-Fuentes, Sirio, et al.
Publicado: (2019)

Hyaluronate supports hESC‐cardiomyocyte cell therapy for cardiac regeneration after acute myocardial infarction
por: Tan, Yuanqing, et al.
Publicado: (2020)

Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies
por: Ji, Tian‐Tian, et al.
Publicado: (2023)

Generation of Myospheres From hESCs by Epigenetic Reprogramming
por: Albini, Sonia, et al.
Publicado: (2014)

Seeding hESCs to achieve optimal colony clonality
por: Wadkin, L. E., et al.
Publicado: (2019)

Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform
por: Weber, Natalie, et al.
Publicado: (2020)

hESC Expansion and Stemness Are Independent of Connexin Forty-Three-Mediated Intercellular Communication between hESCs and hASC Feeder Cells
por: Kim, Jin-Su, et al.
Publicado: (2013)

Generating stable isolated mitochondrial recipient clones in mammalian cells using MitoPunch mitochondrial transfer
por: Sercel, Alexander J., et al.
Publicado: (2021)

Lentiviral Vectors and Protocols for Creation of Stable hESC Lines for Fluorescent Tracking and Drug Resistance Selection of Cardiomyocytes
por: Kita-Matsuo, Hiroko, et al.
Publicado: (2009)

Modulating hESC-derived cardiomyocyte and endothelial cell function with triple-helical peptides for heart tissue engineering
por: Colzani, Maria, et al.
Publicado: (2021)

A Teratocarcinoma-Like Human Embryonic Stem Cell (hESC) Line and Four hESC Lines Reveal Potentially Oncogenic Genomic Changes
por: Hovatta, Outi, et al.
Publicado: (2010)

Demarcation of Stable Subpopulations within the Pluripotent hESC Compartment
por: Bhatia, Sonam, et al.
Publicado: (2013)

Cell viscoelasticity is linked to fluctuations in cell biomass distributions
por: Nguyen, Thang L., et al.
Publicado: (2020)

Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury
por: Gerbin, Kaytlyn A., et al.
Publicado: (2020)

DeephESC 2.0: Deep Generative Multi Adversarial Networks for improving the classification of hESC
por: Theagarajan, Rajkumar, et al.
Publicado: (2019)

Early Acquisition of Neural Crest Competence During hESCs Neuralization
por: Curchoe, Carol Lynn, et al.
Publicado: (2010)

Stabilization of hESCs in two distinct substates along the continuum of pluripotency
por: Dekel, Chen, et al.
Publicado: (2022)

Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines
por: Liu, Ying, et al.
Publicado: (2006)

Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis
por: Yousef, Hanadie, et al.
Publicado: (2014)

Transplantation of hESC-derived hepatocytes protects mice from liver injury
por: Tolosa, Laia, et al.
Publicado: (2015)

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes
por: Cameron, Kate, et al.
Publicado: (2015)

Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors
por: Krentz, Nicole A.J., et al.
Publicado: (2018)

Polysome profiling followed by RNA-seq of cardiac differentiation stages in hESCs
por: Pereira, Isabela Tiemy, et al.
Publicado: (2018)

Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies
por: Ali, Muhammad, et al.
Publicado: (2019)

The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis
por: Griffiths, Rosie, et al.
Publicado: (2020)

Cell maturation influences the ability of hESC-RPE to tolerate cellular stress
por: Viheriälä, Taina, et al.
Publicado: (2022)

Data on cardiac lncRNA STX18-AS1 expression in developing human hearts and function during in vitro hESC-cardiomyocyte differentiation
por: Liu, Yingjuan, et al.
Publicado: (2022)

Ethanol Negatively Regulates Hepatic Differentiation of hESC by Inhibition of the MAPK/ERK Signaling Pathway In Vitro
por: Gao, Wei, et al.
Publicado: (2014)

Specific Marking of hESCs-Derived Hematopoietic Lineage by WAS-Promoter Driven Lentiviral Vectors
por: Muñoz, Pilar, et al.
Publicado: (2012)

hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding
por: Yousef, Hanadie, et al.
Publicado: (2013)

hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
por: Heuer, Andreas, et al.
Publicado: (2016)

Automating hESC differentiation with 3D printing and legacy liquid handling solutions
por: Zluhan, Eric, et al.
Publicado: (2016)

Alternative pre-mRNA splicing switch controls hESC pluripotency and differentiation
por: Agosto, Laura M., et al.
Publicado: (2018)

Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes
por: Hellbach, Nicole, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i12uec8rn470esb5rmomrrfus8