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Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation
Background: Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can be used as a source for cell delivery to remuscularize the heart after myocardial infarction. Despite their therapeutic potential, the emergence of ventricular arrhythmias has limited their application. We previously develop...
Autores principales: | Pezhouman, Arash, Nguyen, Ngoc B., Sercel, Alexander J., Nguyen, Thang L., Daraei, Ali, Sabri, Shan, Chapski, Douglas J., Zheng, Melton, Patananan, Alexander N., Ernst, Jason, Plath, Kathrin, Vondriska, Thomas M., Teitell, Michael A., Ardehali, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722677/ https://www.ncbi.nlm.nih.gov/pubmed/34988079 http://dx.doi.org/10.3389/fcell.2021.787684 |
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