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tRNA biogenesis and specific aminoacyl-tRNA synthetases regulate senescence stability under the control of mTOR

Oncogenes or chemotherapy treatments trigger the induction of suppressive pathways such as apoptosis or senescence. Senescence was initially defined as a definitive arrest of cell proliferation but recent results have shown that this mechanism is also associated with cancer progression and chemother...

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Detalles Bibliográficos
Autores principales: Guillon, Jordan, Coquelet, Hugo, Leman, Géraldine, Toutain, Bertrand, Petit, Coralie, Henry, Cécile, Boissard, Alice, Guette, Catherine, Coqueret, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722728/
https://www.ncbi.nlm.nih.gov/pubmed/34928935
http://dx.doi.org/10.1371/journal.pgen.1009953