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Dynamics of latent HIV under clonal expansion

The HIV latent reservoir exhibits slow decay on antiretroviral therapy (ART), impacted by homeostatic proliferation and activation. How these processes contribute to the total dynamic while also producing the observed profile of sampled latent clone sizes is unclear. An agent-based model was develop...

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Detalles Bibliográficos
Autor principal: Murray, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722732/
https://www.ncbi.nlm.nih.gov/pubmed/34929000
http://dx.doi.org/10.1371/journal.ppat.1010165