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mTORC1 Signaling Pathway Mediates Chronic Stress-Induced Synapse Loss in the Hippocampus

Background: The mechanistic target of rapamycin complex 1 (mTORC1) signaling has served as a promising target for therapeutic intervention of major depressive disorder (MDD), but the mTORC1 signaling underlying MDD has not been well elucidated. In the present study, we investigated whether mTORC1 si...

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Detalles Bibliográficos
Autores principales: Luo, Yu-Fei, Ye, Xiao-Xia, Fang, Ying-Zhao, Li, Meng-Die, Xia, Zhi-Xuan, Liu, Jian-Min, Lin, Xiao-Shan, Huang, Zhen, Zhu, Xiao-Qian, Huang, Jun-Jie, Tan, Dong-Lin, Zhang, Yu-Fei, Liu, Hai-Ping, Zhou, Jun, Shen, Zu-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722735/
https://www.ncbi.nlm.nih.gov/pubmed/34987410
http://dx.doi.org/10.3389/fphar.2021.801234