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DLAB: deep learning methods for structure-based virtual screening of antibodies

MOTIVATION: Antibodies are one of the most important classes of pharmaceuticals, with over 80 approved molecules currently in use against a wide variety of diseases. The drug discovery process for antibody therapeutic candidates however is time- and cost-intensive and heavily reliant on in vivo and...

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Detalles Bibliográficos
Autores principales: Schneider, Constantin, Buchanan, Andrew, Taddese, Bruck, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723137/
https://www.ncbi.nlm.nih.gov/pubmed/34546288
http://dx.doi.org/10.1093/bioinformatics/btab660