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Effect of dose, dosing intervals, and hypoxic stress on the reversal of pulmonary hypertension by mesenchymal stem cell extracellular vesicles

RATIONALE: Mesenchymal stem cell extracellular vesicles (MSC EVs) reverse pulmonary hypertension, but little information is available regarding what dose is effective and how often it needs to be given. This study examined the effects of dose reduction and use of longer dosing intervals and the effe...

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Detalles Bibliográficos
Autores principales: Klinger, James R, Pereira, Mandy, Tatto, Michael Del, Dooner, Mark S, Wen, Sicheng, Quesenberry, Peter J, Liang, Olin D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723172/
https://www.ncbi.nlm.nih.gov/pubmed/34987768
http://dx.doi.org/10.1177/20458940211046137