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A one-step platform for screening high-efficient and minimal off-target CRISPR/Cas13 crRNAs to eradicate SARS-CoV-2 virus for treatment of COVID-19 patients

Coronavirus disease 2019 (COVID-19) is a new respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and now spreads globally. Currently, therapeutics and effective treatment options remain scarce and there is no proven drug to treat COVID-19. Targeting the pos...

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Detalles Bibliográficos
Autores principales: Li, Pu-Yu, Li, San-Qiang, Gao, She-Gan, Dong, Dao-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723761/
https://www.ncbi.nlm.nih.gov/pubmed/35002020
http://dx.doi.org/10.1016/j.mehy.2021.110754