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Bioengineering of Novel Non-Replicating mRNA (NRM) and Self-Amplifying mRNA (SAM) Vaccine Candidates Against SARS-CoV-2 Using Immunoinformatics Approach

Presently, the world needs safe and effective vaccines to overcome the COVID-19 pandemic. Our work has focused on formulating two types of mRNA vaccines that differ in capacity to copy themselves inside the cell. These are non-amplifying mRNA (NRM) and self-amplifying mRNA (SAM) vaccines. Both the v...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Manojit, Sharma, Ashish Ranjan, Ghosh, Pratik, Patra, Prasanta, Patra, Bidhan Chandra, Lee, Sang-Soo, Chakraborty, Chiranjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723807/
https://www.ncbi.nlm.nih.gov/pubmed/34981440
http://dx.doi.org/10.1007/s12033-021-00432-6