DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a neuroendocrine tumor either induced by integration of the Merkel cell polyomavirus into the cell genome or by accumulation of UV-light-associated mutations (VP-MCC and UV-MCC). Whether VP- and UV-MCC have the same or different cellular origins is unclear; with mesenc...

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Detalles Bibliográficos
Autores principales: Gravemeyer, Jan, Spassova, Ivelina, Verhaegen, Monique E., Dlugosz, Andrzej A., Hoffmann, Daniel, Lange, Anja, Becker, Jürgen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724008/
https://www.ncbi.nlm.nih.gov/pubmed/34667274
http://dx.doi.org/10.1038/s41388-021-02064-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724008/
https://www.ncbi.nlm.nih.gov/pubmed/34667274
http://dx.doi.org/10.1038/s41388-021-02064-1

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