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The Pathogenic Roles of IL-22 in Colitis: Its Transcription Regulation by Musculin in T Helper Subsets and Innate Lymphoid Cells

IL-22 plays a crucial role in promoting inflammation, antimicrobial immunity and tissue repair at barrier surfaces. The role of IL-22 in colitis is still controversial: while IL-22 has a protective effect on gut epithelium in acute injuries, it also enhances colitis in a context-dependent manner. He...

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Detalles Bibliográficos
Autores principales: Yan, Jun, Yu, Jing, Liu, Ke, Liu, Yijia, Mao, Changchuin, Gao, Wenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724035/
https://www.ncbi.nlm.nih.gov/pubmed/34992594
http://dx.doi.org/10.3389/fimmu.2021.758730