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Transcriptomic Analysis of Mycobacterium leprae-Stimulated Response in Peripheral Blood Mononuclear Cells Reveal Potential Biomarkers for Early Diagnosis of Leprosy

We aimed to identify an unique host transcriptional signature in peripheral blood mononuclear cells (PBMCs) in response to Mycobacterium leprae antigens to distinguish between patients with leprosy and non-leprosy controls for early diagnosis of the disease. Sixteen individuals were enrolled in the...

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Detalles Bibliográficos
Autores principales: Yuan, You-Hua, Liu, Jian, You, Yuan-Gang, Chen, Xiao-Hua, Yuan, Lian-Chao, Wen, Yan, Li, Huan Ying, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724050/
https://www.ncbi.nlm.nih.gov/pubmed/34993156
http://dx.doi.org/10.3389/fcimb.2021.714396