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Integrative analysis of the 3D genome structure reveals that CTCF maintains the properties of mouse female germline stem cells

The three-dimensional configuration of the genome ensures cell type-specific gene expression profiles by placing genes and regulatory elements in close spatial proximity. Here, we used in situ high-throughput chromosome conformation (in situ Hi-C), RNA sequencing (RNA-seq) and chromatin immunoprecip...

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Detalles Bibliográficos
Autores principales: Tian, Geng G., Zhao, Xinyan, Hou, Changliang, Xie, Wenhai, Li, Xiaoyong, Wang, Yinjuan, Wang, Lijuan, Li, Hua, Zhao, Xiaodong, Li, Jing, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724064/
https://www.ncbi.nlm.nih.gov/pubmed/34981210
http://dx.doi.org/10.1007/s00018-021-04107-y