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Integrative analysis of the 3D genome structure reveals that CTCF maintains the properties of mouse female germline stem cells
The three-dimensional configuration of the genome ensures cell type-specific gene expression profiles by placing genes and regulatory elements in close spatial proximity. Here, we used in situ high-throughput chromosome conformation (in situ Hi-C), RNA sequencing (RNA-seq) and chromatin immunoprecip...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724064/ https://www.ncbi.nlm.nih.gov/pubmed/34981210 http://dx.doi.org/10.1007/s00018-021-04107-y |