Immune checkpoint inhibitor treatment induces colitis with heavy infiltration of CD8 + T cells and an infiltration pattern that resembles ulcerative colitis

Colitis is a common, but poorly understood, adverse event of immune checkpoint inhibitors that are standard-of-care for an expanding range of cancer types. This explorative study aimed to describe the immune infiltrates in the colon from individuals developing checkpoint inhibitor colitis and compar...

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Detalles Bibliográficos
Autores principales: Hone Lopez, Sara, Kats-Ugurlu, Gursah, Renken, Remco J., Buikema, Henk J., de Groot, Marco R., Visschedijk, Marijn C., Dijkstra, Gerard, Jalving, Mathilde, de Haan, Jacco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724151/
https://www.ncbi.nlm.nih.gov/pubmed/34338882
http://dx.doi.org/10.1007/s00428-021-03170-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724151/
https://www.ncbi.nlm.nih.gov/pubmed/34338882
http://dx.doi.org/10.1007/s00428-021-03170-x

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