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Artificial Neural Network Analysis-Based Immune-Related Signatures of Primary Non-Response to Infliximab in Patients With Ulcerative Colitis

Infliximab (IFX) is an effective medication for ulcerative colitis (UC) patients. However, one-third of UC patients show primary non-response (PNR) to IFX. Our study analyzed three Gene Expression Omnibus (GEO) datasets and used the RobustRankAggreg (RRA) algorithm to assist in identifying different...

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Detalles Bibliográficos
Autores principales: Chen, Xuanfu, Jiang, Lingjuan, Han, Wei, Bai, Xiaoyin, Ruan, Gechong, Guo, Mingyue, Zhou, Runing, Liang, Haozheng, Yang, Hong, Qian, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724249/
https://www.ncbi.nlm.nih.gov/pubmed/34992592
http://dx.doi.org/10.3389/fimmu.2021.742080