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Functional Verification of Novel ELMO1 Variants by Live Imaging in Zebrafish

ELMO1 (Engulfment and Cell Motility1) is a gene involved in regulating cell motility through the ELMO1-DOCK2-RAC complex. Contrary to DOCK2 (Dedicator of Cytokinesis 2) deficiency, which has been reported to be associated with immunodeficiency diseases, variants of ELMO1 have been associated with au...

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Detalles Bibliográficos
Autores principales: Xue, Rongtao, Wang, Ying, Wang, Tienan, Lyu, Mei, Mo, Guiling, Fan, Xijie, Li, Jianchao, Yen, Kuangyu, Yu, Shihui, Liu, Qifa, Xu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724260/
https://www.ncbi.nlm.nih.gov/pubmed/34993193
http://dx.doi.org/10.3389/fcell.2021.723804