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Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice

Treatment with aprotinin, a broad-spectrum serine protease inhibitor with a molecular weight of 6512 Da, was associated with acute kidney injury, which was one of the reasons for withdrawal from the market in 2007. Inhibition of renal serine proteases regulating the epithelial sodium channel ENaC co...

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Detalles Bibliográficos
Autores principales: Wörner, Stefan, Bohnert, Bernhard N., Wörn, Matthias, Xiao, Mengyun, Janessa, Andrea, Birkenfeld, Andreas L., Amann, Kerstin, Daniel, Christoph, Artunc, Ferruh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724274/
https://www.ncbi.nlm.nih.gov/pubmed/33758357
http://dx.doi.org/10.1038/s41401-021-00628-1