Cepharanthine sensitizes human triple negative breast cancer cells to chemotherapeutic agent epirubicin via inducing cofilin oxidation-mediated mitochondrial fission and apoptosis

Inhibition of autophagy has been accepted as a promising therapeutic strategy in cancer, but its clinical application is hindered by lack of effective and specific autophagy inhibitors. We previously identified cepharanthine (CEP) as a novel autophagy inhibitor, which inhibited autophagy/mitophagy t...

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Detalles Bibliográficos
Autores principales: Shen, Li-wen, Jiang, Xiu-xing, Li, Zhi-qiang, Li, Jie, Wang, Mei, Jia, Guan-fei, Ding, Xin, Lei, Ling, Gong, Qi-hai, Gao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724299/
https://www.ncbi.nlm.nih.gov/pubmed/34294886
http://dx.doi.org/10.1038/s41401-021-00715-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724299/
https://www.ncbi.nlm.nih.gov/pubmed/34294886
http://dx.doi.org/10.1038/s41401-021-00715-3

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