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Marked increase in tumor transfection with a truncated branched polymer

BACKGROUND: We previously determined that polyplexes formed by linear H2K peptides were more effective in transfecting tumors in vivo than polyplexes formed by branched H2K4b‐20 peptides. Based on trypsin digest and salt displacement studies, the linear H2K polyplexes were less stable than the branc...

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Detalles Bibliográficos
Autores principales: Xu, Songhui, He, Jiaxi, Imtiyaz, Zuha, Agrawal, Atul K., Woodle, Martin C., Mixson, A. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724455/
https://www.ncbi.nlm.nih.gov/pubmed/34713552
http://dx.doi.org/10.1002/jgm.3396