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Adaptive laboratory evolution triggers pathogen-dependent broad-spectrum antimicrobial potency in Streptomyces

BACKGROUND: In the present study, adaptive laboratory evolution was used to stimulate antibiotic production in a Streptomyces strain JB140 (wild-type) exhibiting very little antimicrobial activity against bacterial pathogens. The seven different competition experiments utilized three serial passages...

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Detalles Bibliográficos
Autores principales: Harwani, Dharmesh, Begani, Jyotsna, Barupal, Sweta, Lakhani, Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724467/
https://www.ncbi.nlm.nih.gov/pubmed/34978647
http://dx.doi.org/10.1186/s43141-021-00283-3