Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models

Large-scale clinical outcome studies demonstrated the efficacy of SGLT2 inhibitors in patients with type II diabetes. Besides their therapeutic efficacy in diabetes, significant renoprotection was observed in non-diabetic patients with chronic kidney disease (CKD), suggesting the existence of glucos...

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Detalles Bibliográficos
Autores principales: Tauber, Philipp, Sinha, Frederick, Berger, Raffaela S., Gronwald, Wolfram, Dettmer, Katja, Kuhn, Michaela, Trum, Maximilian, Maier, Lars S., Wagner, Stefan, Schweda, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724563/
https://www.ncbi.nlm.nih.gov/pubmed/34992532
http://dx.doi.org/10.3389/fphar.2021.761855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724563/
https://www.ncbi.nlm.nih.gov/pubmed/34992532
http://dx.doi.org/10.3389/fphar.2021.761855

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