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Sequential immunization with SARS-CoV-2 RBD vaccine induces potent and broad neutralization against variants in mice

The current COVID-19 pandemic caused by constantly emerging SARS-CoV-2 variants still poses a threat to public health worldwide. Effective next-generation vaccines and optimized booster vaccination strategies are urgently needed. Here, we sequentially immunized mice with a SARS-CoV-2 wild-type inact...

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Detalles Bibliográficos
Autores principales: Song, Shuo, Zhou, Bing, Cheng, Lin, Liu, Weilong, Fan, Qing, Ge, Xiangyang, Peng, Hua, Fu, Yang-Xin, Ju, Bin, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724645/
https://www.ncbi.nlm.nih.gov/pubmed/34983583
http://dx.doi.org/10.1186/s12985-021-01737-3