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Reflux of Endoplasmic Reticulum proteins to the cytosol inactivates tumor suppressors

In the past decades, many studies reported the presence of endoplasmic reticulum (ER)‐resident proteins in the cytosol. However, the mechanisms by which these proteins relocate and whether they exert cytosolic functions remain unknown. We find that a subset of ER luminal proteins accumulates in the...

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Detalles Bibliográficos
Autores principales: Sicari, Daria, Centonze, Federica G, Pineau, Raphael, Le Reste, Pierre‐Jean, Negroni, Luc, Chat, Sophie, Mohtar, M Aiman, Thomas, Daniel, Gillet, Reynald, Hupp, Ted, Chevet, Eric, Igbaria, Aeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724677/
https://www.ncbi.nlm.nih.gov/pubmed/33710763
http://dx.doi.org/10.15252/embr.202051412