BMP4 micro‐immunotherapy increases collagen deposition and reduces PGE2 release in human gingival fibroblasts and increases tissue viability of engineered 3D gingiva under inflammatory conditions

BACKGROUND: We aimed to evaluate the effect of low doses (LD) bone morphogenetic protein‐2 (BMP2) and BMP4 micro‐immunotherapy (MI) in two in vitro models of periodontal wound healing/regeneration. METHODS: We first evaluated the effect of LD of BMP2 and BMP4 MI on a 2D cell culture using human ging...

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Detalles Bibliográficos
Autores principales: Ferrà‐Cañellas, Maria del Mar, Munar‐Bestard, Marta, Garcia‐Sureda, Laura, Lejeune, Beatrice, Ramis, Joana Maria, Monjo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Translational Periodontology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724682/
https://www.ncbi.nlm.nih.gov/pubmed/33393105
http://dx.doi.org/10.1002/JPER.20-0552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724682/
https://www.ncbi.nlm.nih.gov/pubmed/33393105
http://dx.doi.org/10.1002/JPER.20-0552

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