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Exon‐independent recruitment of SRSF1 is mediated by U1 snRNP stem‐loop 3

SRSF1 protein and U1 snRNPs are closely connected splicing factors. They both stimulate exon inclusion, SRSF1 by binding to exonic splicing enhancer sequences (ESEs) and U1 snRNPs by binding to the downstream 5′ splice site (SS), and both factors affect 5′ SS selection. The binding of U1 snRNPs init...

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Detalles Bibliográficos
Autores principales: Jobbins, Andrew M, Campagne, Sébastien, Weinmeister, Robert, Lucas, Christian M, Gosliga, Alison R, Clery, Antoine, Chen, Li, Eperon, Lucy P, Hodson, Mark J, Hudson, Andrew J, Allain, Frédéric H T, Eperon, Ian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724738/
https://www.ncbi.nlm.nih.gov/pubmed/34779515
http://dx.doi.org/10.15252/embj.2021107640