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Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron‐enriched genes

In mammals, histone 3 lysine 4 methylation (H3K4me) is mediated by six different lysine methyltransferases. Among these enzymes, SETD1B (SET domain containing 1b) has been linked to syndromic intellectual disability in human subjects, but its role in the mammalian postnatal brain has not been studie...

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Detalles Bibliográficos
Autores principales: Michurina, Alexandra, Sakib, M Sadman, Kerimoglu, Cemil, Krüger, Dennis Manfred, Kaurani, Lalit, Islam, Md Rezaul, Joshi, Parth Devesh, Schröder, Sophie, Centeno, Tonatiuh Pena, Zhou, Jiayin, Pradhan, Ranjit, Cha, Julia, Xu, Xingbo, Eichele, Gregor, Zeisberg, Elisabeth M, Kranz, Andrea, Stewart, A Francis, Fischer, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724770/
https://www.ncbi.nlm.nih.gov/pubmed/34806773
http://dx.doi.org/10.15252/embj.2020106459