OASL1-Mediated Inhibition of Type I IFN Reduces Influenza A Infection-Induced Airway Inflammation by Regulating ILC2s

PURPOSE: Three observations drove this study. First, 2′-5′-oligoadenylate synthetase-like protein (OASL) is a negative regulator of type I interferon (IFN). Second, type I IFN plays a central role during virus infections and the pathogenesis of various diseases, including asthma. Third, influenza A...

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Detalles Bibliográficos
Autores principales: Chang, Yuna, Kang, Ji-Seon, Jung, Keehoon, Chung, Doo Hyun, Ha, Sang-Jun, Kim, Young-Joon, Kim, Hye Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724833/
https://www.ncbi.nlm.nih.gov/pubmed/34983110
http://dx.doi.org/10.4168/aair.2022.14.1.99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724833/
https://www.ncbi.nlm.nih.gov/pubmed/34983110
http://dx.doi.org/10.4168/aair.2022.14.1.99

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