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OASL1-Mediated Inhibition of Type I IFN Reduces Influenza A Infection-Induced Airway Inflammation by Regulating ILC2s
PURPOSE: Three observations drove this study. First, 2′-5′-oligoadenylate synthetase-like protein (OASL) is a negative regulator of type I interferon (IFN). Second, type I IFN plays a central role during virus infections and the pathogenesis of various diseases, including asthma. Third, influenza A...
Autores principales: | Chang, Yuna, Kang, Ji-Seon, Jung, Keehoon, Chung, Doo Hyun, Ha, Sang-Jun, Kim, Young-Joon, Kim, Hye Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724833/ https://www.ncbi.nlm.nih.gov/pubmed/34983110 http://dx.doi.org/10.4168/aair.2022.14.1.99 |
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