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Inhibition of Cytochrome P450 Enzymes by Drugs—Molecular Basis and Practical Applications
Drug-drug interactions are a major cause of hospitalization and deaths related to drug use. A large fraction of these is due to inhibition of enzymes involved in drug metabolism and transport, particularly cytochrome P450 (P450) enzymes. Understanding basic mechanisms of enzyme inhibition is importa...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Society of Applied Pharmacology
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724836/ https://www.ncbi.nlm.nih.gov/pubmed/34475272 http://dx.doi.org/10.4062/biomolther.2021.102 |