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Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice
The present study focused on lithocholic acid (LCA), a secondary bile acid that contributes to cholestatic pruritus. Although recent studies have found that LCA acts on MAS-related G protein-coupled receptor family member X4 (MRGPRX4) in humans, it is unclear which subtypes of MRGPRs are activated b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Society of Applied Pharmacology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724838/ https://www.ncbi.nlm.nih.gov/pubmed/34263729 http://dx.doi.org/10.4062/biomolther.2021.059 |