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Melatonin Protects Chronic Kidney Disease Mesenchymal Stem/Stromal Cells against Accumulation of Methylglyoxal via Modulation of Hexokinase-2 Expression

Treatment options for patients with chronic kidney disease (CKD) are currently limited; therefore, there has been significant interest in applying mesenchymal stem/stromal cell (MSC)-based therapy to treat CKD. However, MSCs harvested from CKD patients tend to show diminished viability and prolifera...

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Detalles Bibliográficos
Autores principales: Go, Gyeongyun, Yoon, Yeo Min, Yoon, Sungtae, Lee, Gaeun, Lim, Ji Ho, Han, Su-Yeon, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724841/
https://www.ncbi.nlm.nih.gov/pubmed/34261819
http://dx.doi.org/10.4062/biomolther.2021.058