Cargando…

Chronicles of EGFR Tyrosine Kinase Inhibitors: Targeting EGFR C797S Containing Triple Mutations

Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase widely expressed in many cancers such as non-small cell lung cancer (NSCLC), pancreatic cancer, breast cancer, and head and neck cancer. Mutations such as L858R in exon 21, exon 19 truncation (Del19), exon 20 insertions, and other...

Descripción completa

Detalles Bibliográficos
Autores principales: Duggirala, Krishna Babu, Lee, Yujin, Lee, Kwangho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724843/
https://www.ncbi.nlm.nih.gov/pubmed/34074804
http://dx.doi.org/10.4062/biomolther.2021.047