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Allele-Specific Thresholds of Eluted Ligands for T-Cell Epitope Prediction

A common strategy for predicting candidate human leukocyte antigen class I T-cell epitopes is to use an affinity-based threshold of 500 nM. Although a 500 nM threshold across alleles effectively identifies most epitopes across alleles, findings showing that major histocompatibility complex repertoir...

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Detalles Bibliográficos
Autores principales: Reardon, Brian, Koşaloğlu-Yalçın, Zeynep, Paul, Sinu, Peters, Bjoern, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724920/
https://www.ncbi.nlm.nih.gov/pubmed/34303001
http://dx.doi.org/10.1016/j.mcpro.2021.100122