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Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis

BACKGROUND: Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. Here we explore the use of sAXL as a biomarker for PDAC. METHODS: AXL was analysed by...

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Detalles Bibliográficos
Autores principales: Martínez-Bosch, Neus, Cristóbal, Helena, Iglesias, Mar, Gironella, Meritxell, Barranco, Luis, Visa, Laura, Calafato, Domenico, Jiménez-Parrado, Silvia, Earl, Julie, Carrato, Alfredo, Manero-Rupérez, Noemí, Moreno, Mireia, Morales, Albert, Guerra, Carmen, Navarro, Pilar, García de Frutos, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724936/
https://www.ncbi.nlm.nih.gov/pubmed/34973624
http://dx.doi.org/10.1016/j.ebiom.2021.103797