Photo-activated proflavine degrades protein and impairs enzyme activity: Involvement of hydroxyl radicals

Proflavine is a well-known antiseptic and bacteriostatic drug, however, it has the potential to be hazardous and mutagenic. Proflavine enters cells and intercalates between DNA base pairs, resulting in mutation and replication inhibition. Previously several investigators demonstrated that photo-acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghatasheh, Mansour K., Malik, Abdul, Ola, Mohammad Shamsul, Alhomida, Abdullah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724948/
https://www.ncbi.nlm.nih.gov/pubmed/35024344
http://dx.doi.org/10.1016/j.toxrep.2021.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724948/
https://www.ncbi.nlm.nih.gov/pubmed/35024344
http://dx.doi.org/10.1016/j.toxrep.2021.12.009

Ejemplares similares