Cargando…
Photo-activated proflavine degrades protein and impairs enzyme activity: Involvement of hydroxyl radicals
Proflavine is a well-known antiseptic and bacteriostatic drug, however, it has the potential to be hazardous and mutagenic. Proflavine enters cells and intercalates between DNA base pairs, resulting in mutation and replication inhibition. Previously several investigators demonstrated that photo-acti...
Autores principales: | Ghatasheh, Mansour K., Malik, Abdul, Ola, Mohammad Shamsul, Alhomida, Abdullah S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724948/ https://www.ncbi.nlm.nih.gov/pubmed/35024344 http://dx.doi.org/10.1016/j.toxrep.2021.12.009 |
Ejemplares similares
-
THE ACCELERATION OF SAPONIN HEMOLYSIS BY PROFLAVINE
por: Collier, H. Bruce
Publicado: (1945) -
Neurodegeneration in Diabetic Retina and Its Potential Drug Targets
por: Ola, Mohammad Shamsul, et al.
Publicado: (2014) -
Antiseptic Action of Acriflavine, Proflavine and Brilliant Green
Publicado: (1918) -
Modulation of the Structure and Stability of Novel Camel Lens Alpha-Crystallin by pH and Thermal Stress
por: Malik, Ajamaluddin, et al.
Publicado: (2022) -
Synthesis of Novel Biologically Active Proflavine Ureas Designed on the Basis of Predicted Entropy Changes
por: Janovec, Ladislav, et al.
Publicado: (2021)