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Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin. However, the topology of this interaction and its consequences on neuronal function remain une...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724971/ https://www.ncbi.nlm.nih.gov/pubmed/35024577 http://dx.doi.org/10.1016/j.isci.2021.103621 |