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Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin. However, the topology of this interaction and its consequences on neuronal function remain une...

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Detalles Bibliográficos
Autores principales: Marty, Florent Henri, Bettamin, Luca, Thouard, Anne, Bourgade, Karine, Allart, Sophie, Larrieu, Guilhem, Malnou, Cécile Evelyne, Gonzalez-Dunia, Daniel, Suberbielle, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724971/
https://www.ncbi.nlm.nih.gov/pubmed/35024577
http://dx.doi.org/10.1016/j.isci.2021.103621