Cryotrapping peroxide in the active site of human mitochondrial manganese superoxide dismutase crystals for neutron diffraction

Structurally identifying the enzymatic intermediates of redox proteins has been elusive due to difficulty in resolving the H atoms involved in catalysis and the susceptibility of ligand complexes to photoreduction from X-rays. Cryotrapping ligands for neutron protein crystallography combines two pow...

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Detalles Bibliográficos
Autores principales: Azadmanesh, Jahaun, Lutz, William E., Coates, Leighton, Weiss, Kevin L., Borgstahl, Gloria E. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725007/
https://www.ncbi.nlm.nih.gov/pubmed/34981770
http://dx.doi.org/10.1107/S2053230X21012413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725007/
https://www.ncbi.nlm.nih.gov/pubmed/34981770
http://dx.doi.org/10.1107/S2053230X21012413

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