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Engineered small extracellular vesicles displaying ACE2 variants on the surface protect against SARS‐CoV‐2 infection

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) entry is mediated by the interaction of the viral spike (S) protein with angiotensin‐converting enzyme 2 (ACE2) on the host cell surface. Although a clinical trial testing soluble ACE2 (sACE2) for COVID‐19 is currently ongoing, our underst...

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Detalles Bibliográficos
Autores principales: Kim, Hark Kyun, Cho, Junhyung, Kim, Eunae, Kim, Junsik, Yang, Jeong‐Sun, Kim, Kyung‐Chang, Lee, Joo‐Yeon, Shin, Younmin, Palomera, Leon F., Park, Jinsu, Baek, Seung Hyun, Bae, Han‐Gyu, Cho, Yoonsuk, Han, Jihoon, Sul, Jae Hoon, Lee, Jeongmi, Park, Jae Hyung, Cho, Yong Woo, Lee, Wonsik, Jo, Dong‐Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725171/
https://www.ncbi.nlm.nih.gov/pubmed/34982509
http://dx.doi.org/10.1002/jev2.12179