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Expression of therapy-induced senescence markers in breast cancer samples upon incomplete response to neoadjuvant chemotherapy

Senescence is a cell stress response induced by replicative, oxidative, oncogenic, and genotoxic stresses. Tumor cells undergo senescence in response to several cancer therapeutics in vitro (Therapy-Induced Senescence, TIS), including agents utilized as neoadjuvant chemotherapy (NAC) in the treatmen...

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Detalles Bibliográficos
Autores principales: Saleh, Tareq, Alhesa, Ahmad, Al-Balas, Mahmoud, Abuelaish, Omar, Mansour, Ahmad, Awad, Heyam, El-Sadoni, Mohammed, Carpenter, Valerie J., Azab, Bilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725197/
https://www.ncbi.nlm.nih.gov/pubmed/33948615
http://dx.doi.org/10.1042/BSR20210079