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Splenic CD4(+) and CD8(+) T-cells highly expressed PD-1 and Tim-3 in cirrhotic patients with HCV infection and portal hypertension

Introduction: The spleen plays an important role in regulating the immune response to infectious pathogens. T-cells dysfunction and exhaustion have been reported in patients with hepatitis B/C virus (HBV/HCV) infection, which contributes to persistent virus infection. The aims of this study were to...

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Detalles Bibliográficos
Autores principales: Huang, Na, Zhou, Rui, Chen, Haiyan, Zhang, Shu, Li, Jun, Wei, Wei, Sun, Jin, Ren, Song, Li, Baohua, Deng, Hong, Yang, Jun, Ji, Fanpu, Li, Zongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725229/
https://www.ncbi.nlm.nih.gov/pubmed/34930041
http://dx.doi.org/10.1177/20587384211061051