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miR-653-5p suppresses the viability and migration of fibroblast-like synoviocytes by targeting FGF2 and inactivation of the Wnt/beta-catenin pathway

BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. Several studies reported that fibroblast-like synoviocytes (FLSs) and miRNAs are associated with RA pathogenesis. This study explored the function of miR-653-5p in the regulation of human fibroblast-like synoviocytes-rhe...

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Detalles Bibliográficos
Autores principales: Dong, Peilong, Tang, Xiaobo, Wang, Jian, Zhu, Botao, Li, Zhiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725305/
https://www.ncbi.nlm.nih.gov/pubmed/34983591
http://dx.doi.org/10.1186/s13018-021-02887-4