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Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System

BACKGROUND: Because some of its CNS neurons (e.g., retinal ganglion cells after optic nerve crush (ONC)) regenerate axons throughout life, whereas others (e.g., hindbrain neurons after spinal cord injury (SCI)) lose this capacity as tadpoles metamorphose into frogs, the South African claw-toed frog,...

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Detalles Bibliográficos
Autores principales: Reverdatto, Sergei, Prasad, Aparna, Belrose, Jamie L., Zhang, Xiang, Sammons, Morgan A., Gibbs, Kurt M., Szaro, Ben G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725369/
https://www.ncbi.nlm.nih.gov/pubmed/34979916
http://dx.doi.org/10.1186/s12864-021-08247-0