Conjugation of VEGFR1/R2-targeting peptide with gold nanoparticles to enhance antiangiogenic and antitumoral activity

BACKGROUND: Inhibition of tumor angiogenesis through simultaneous targeting of vascular endothelial growth factor receptor (VEGFR)-1 and -2 is highly efficacious. An antagonist peptide of VEGFA/VEGFB, referred to as VGB3, can recognize and neutralize both VEGFR1 and VEGFR2 on the endothelial and tum...

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Detalles Bibliográficos
Autores principales: Zanjanchi, Pegah, Asghari, S. Mohsen, Mohabatkar, Hassan, Shourian, Mostafa, Shafiee Ardestani, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725421/
https://www.ncbi.nlm.nih.gov/pubmed/34983556
http://dx.doi.org/10.1186/s12951-021-01198-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8725421/
https://www.ncbi.nlm.nih.gov/pubmed/34983556
http://dx.doi.org/10.1186/s12951-021-01198-4

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